Idiopathic giant scrotal calcinosis: a rare case report and literature review

Wyckmell Octof Ingratoeboen; Gerhard Reinaldi Situmorang; Riesye Arisanty; Madhyra Tri Indraswari; Ponco Birowo

doi:10.15562/bmj.v12i3.4608

Idiopathic giant scrotal calcinosis: a rare case report and literature review

Wyckmell Octof Ingratoeboen ,

Gerhard Reinaldi Situmorang ,

Riesye Arisanty ,

Madhyra Tri Indraswari ,

Ponco Birowo ,

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DOI: https://doi.org/10.15562/bmj.v12i3.4608 |
Published: 2023-08-10

Abstract

Link of Video Abstract: https://youtu.be/HwWU4JYsovA

Background: Scrotal calcinosis is a rare abnormality of external genitalia. To date, the pathogenesis of this con is still debated. However, reconstructive surgical therapy is still the treatment of choice in managing this disease. This case report presents our experience in performing extensive excision followed by reconstruction of scrotal defects in patients diagnosed with scrotal calcinosis.

Case Presentation: A 62-year-old healthy man was referred to our department with multiple nodules on the testicular sac that did not cause symptoms but began to disrupt his quality of life. The diagnosis was made by physical examination, and anatomic pathology examination results from a needle biopsy that had been done before. Extensive excision of the scrotum lesion was followed by defect closure. There were no significant intraoperative or postoperative. The procedure was uneventful, and the reconstruction results showed satisfying results.

Conclusion: Scrotal calcinosis is an uncommon skin disease caused by insoluble calcium salts accumulated in scrotal skin tissue. Although the origin and etiology of scrotal calcinosis are debatable, surgical excision is the preferred treatment with a low recurrence rate and good cosmetic results.

References

Yilmaz R, Sehitoglu I, Eren H, Murtezaoglu AR, Bedir R. Twenty Scrotal Nodules of Idiopathic Calcinosis : A Case Report. 2015;4(2):7–9.
Syed MM, Rajbhandari A, Paudel U. Idiopathic calcinosis cutis of the scrotum: a case report and review of the literature. J Med Case Reports. 2018;12(1):1-5.
Ye D, Ma X, Yang X. Scrotal calcinosis: a case report and literature review. Am J Clin Exp Urol. 2022;10(3):194-198.
Dubey S, Sharma R, Maheshwari V. Scrotal calcinosis: idiopathic or dystrophic? Dermatol Online J. 2010;16(2):5.
Khallouk A, Yazami O El, Mellas S. Idiopathic Scrotal Calcinosis : A Non-Elucidated Pathogenesis. 2011;13(2):95–97.
Angus W, Mistry R, Floyd MS, Machin DG. Multiple large infected scrotal sebaceous cysts masking Fournier’s gangrene in a 32-year-old man. BMJ Case Rep. 2012;2012:bcr1120115253.
Rahman MH, Islam MS, Ansari NP. Atypical Steatocystoma Multiplex with Calcification. ISRN Dermatol. 2011;2011:1–3.
Solanki A, Narang S, Kathpalia R, Goel A. Scrotal calcinosis: Pathogenetic link with epidermal Cyst. BMJ Case Rep. 2015;2015:1–3.
Yuyucu Karabulut Y, Kankaya D, Şenel E, Dölek Y, Uslu A, Sertçelik A. Idiopathic scrotal calcinosis: the incorrect terminology of scrotal calcinosis. G Ital Dermatol Venereol. 2015;150(5):495-499.
Andola SK, Tandon T, Patil AG. Clinical-epidemiological, cytological and histopathological study of idiopathic calcinosis cutis of the scrotum. J Clin Diagnostic Res. 2017;11(11):EC01–EC04.
Salvarci A, Altinay S. Relapsing idiopathic scrotal calcinosis. J Pak Med Assoc. 2013;63(11):1433–1434.
Prabawa IPY, Bhargah A, Liwang F, Tandio DA, Tandio AL, Lestari AAW, et al. Pretreatment neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) as a predictive value of hematological markers in cervical cancer. Asian Pacific journal of cancer prevention: APJCP. 2019;20(3):863-868.
Ringoringo DRL, Nasution R, Adhyatma KP. A single-stage reconstruction on giant scrotal lymphedema: a case report. Bali Medical Journal. 2022;11(1):387–390.
Soebhali B. Sclerosing lipogranuloma of the penis: a review of management and classification. Bali Medical Journal. 2020;9(1):55–61.
Dahril D, Manurun F, Pratama R. Penile necrosis due to calciphylaxis in peritoneal dyalisis patient: a case report. Bali Medical Journal. 2020;9(1):163–166.
Noel W, Hersant B, Meningaud J-P. One-staged surgical technique for scrotal calcinosis. Prog Urol. 2016;26(3):176–180.
Mardi K. Multiple scrotal epidermal cysts: A rare case report. J Clin Sci. 2014;11(1):20.
Meissner M, Kleemann J, Kaufmann R, Ochsendorf F. The erbium:YAG Laser: a new technique for the treatment of scrotal calcinosis. J Eur Acad Dermatology Venereol. 2017;31(4):e207–209.
AlGhamdi KM, AlEnazi MM. Versatile punch surgery. J Cutan Med Surg. 2011;15(2):87–96.

[1] Yilmaz R, Sehitoglu I, Eren H, Murtezaoglu AR, Bedir R. Twenty Scrotal Nodules of Idiopathic Calcinosis : A Case Report. 2015;4(2):7–9.

[2] Syed MM, Rajbhandari A, Paudel U. Idiopathic calcinosis cutis of the scrotum: a case report and review of the literature. J Med Case Reports. 2018;12(1):1-5.

[3] Ye D, Ma X, Yang X. Scrotal calcinosis: a case report and literature review. Am J Clin Exp Urol. 2022;10(3):194-198.

[4] Dubey S, Sharma R, Maheshwari V. Scrotal calcinosis: idiopathic or dystrophic? Dermatol Online J. 2010;16(2):5.

[5] Khallouk A, Yazami O El, Mellas S. Idiopathic Scrotal Calcinosis : A Non-Elucidated Pathogenesis. 2011;13(2):95–97.

[6] Angus W, Mistry R, Floyd MS, Machin DG. Multiple large infected scrotal sebaceous cysts masking Fournier’s gangrene in a 32-year-old man. BMJ Case Rep. 2012;2012:bcr1120115253.

[7] Rahman MH, Islam MS, Ansari NP. Atypical Steatocystoma Multiplex with Calcification. ISRN Dermatol. 2011;2011:1–3.

[8] Solanki A, Narang S, Kathpalia R, Goel A. Scrotal calcinosis: Pathogenetic link with epidermal Cyst. BMJ Case Rep. 2015;2015:1–3.

[9] Yuyucu Karabulut Y, Kankaya D, Şenel E, Dölek Y, Uslu A, Sertçelik A. Idiopathic scrotal calcinosis: the incorrect terminology of scrotal calcinosis. G Ital Dermatol Venereol. 2015;150(5):495-499.

[10] Andola SK, Tandon T, Patil AG. Clinical-epidemiological, cytological and histopathological study of idiopathic calcinosis cutis of the scrotum. J Clin Diagnostic Res. 2017;11(11):EC01–EC04.

[11] Salvarci A, Altinay S. Relapsing idiopathic scrotal calcinosis. J Pak Med Assoc. 2013;63(11):1433–1434.

[12] Prabawa IPY, Bhargah A, Liwang F, Tandio DA, Tandio AL, Lestari AAW, et al. Pretreatment neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) as a predictive value of hematological markers in cervical cancer. Asian Pacific journal of cancer prevention: APJCP. 2019;20(3):863-868.

[13] Ringoringo DRL, Nasution R, Adhyatma KP. A single-stage reconstruction on giant scrotal lymphedema: a case report. Bali Medical Journal. 2022;11(1):387–390.

[14] Soebhali B. Sclerosing lipogranuloma of the penis: a review of management and classification. Bali Medical Journal. 2020;9(1):55–61.

[15] Dahril D, Manurun F, Pratama R. Penile necrosis due to calciphylaxis in peritoneal dyalisis patient: a case report. Bali Medical Journal. 2020;9(1):163–166.

[16] Noel W, Hersant B, Meningaud J-P. One-staged surgical technique for scrotal calcinosis. Prog Urol. 2016;26(3):176–180.

[17] Mardi K. Multiple scrotal epidermal cysts: A rare case report. J Clin Sci. 2014;11(1):20.

[18] Meissner M, Kleemann J, Kaufmann R, Ochsendorf F. The erbium:YAG Laser: a new technique for the treatment of scrotal calcinosis. J Eur Acad Dermatology Venereol. 2017;31(4):e207–209.

[19] AlGhamdi KM, AlEnazi MM. Versatile punch surgery. J Cutan Med Surg. 2011;15(2):87–96.

Idiopathic giant scrotal calcinosis: a rare case report and literature review

Abstract

References

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