Objectives: Lactate is one of the prognostic factor for evaluation of clinical severe head injury patientsÂ outcome. Lactate is also known as a factor to support diagnostic and prognosis of SIRS cases. SevereÂ head injury is a head traumatic case frequently found in Emergency Units, where some cases result inÂ mortality. Based on Glasgow Coma Scale (GCS), severe head injury is define as a head injury with GCS
score between 3 and 8. This study aims to determine whether high arterial blood lactate can be used asÂ predictor that causes the occurrence of SIRS.
Method:Â A Cohort prospective study applied in this
research to determine arterial blood lactate as a predictor that causes the occurrence of SIRS. This studyÂ was conducted at Sanglah General Hospital Bali-Indonesia from May 2013 to July 2013 with 40 patientsÂ who fulfilled the inclusive criteria. Data were presented in tables and analyzed by applying Chi SquareÂ Test with CI 95% and p <0.05 was considered significant.
Results: From 40 samples, 27 were maleÂ (62.5%) and 17 female (37.5%) at the age of 0-10, 2 people (5%), 10-20 years 7 people (17.5%), 20-40Â years 14 people (35%), 40-60 years 12 people (30%) and over 60 years 5 people (12.5%). On the firstÂ day, patients with normal level blood arterial lactate 2 (5%), and high 38 (95%) causing SIRS (+) 39Â (97.5%) and SIRS (-) 1 (2.5%) samples to occur. Using bivariate analysis between arterial blood lactateÂ level and the amount occurrence of SIRS, we obtain p < 0.05 and variable control using multivariateÂ analysis we obtained variable of liver dysfunction that give significant value with level arterial bloodÂ lactate with p < 0.05).
Conclusion: From 40 samples of Severe head injury, there were 38 (95%) whoseÂ blood arterial lactate level increased on the first day, 2 (5%) in normal limit and 39 (97.5%) with SIRS onÂ the third day when p < 0.05) so that high level arterial blood lactate can be used as predictor that causesÂ SIRS to occur.