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Supplementation of Moringa (Moringa oleifera) leaf capsules on hemoglobin levels in women of reproductive age with iron deficiency anemia in Malaka regency, Nusa Tenggara Timur, Indonesia

Abstract

Link of Video Abstract: https://youtu.be/DjGx56j9LiU

 

Introduction: Women of reproductive age with anemia are recommended to take iron supplements and increase their intake of iron-rich food. Moringa (Moringa oleifera) leaf is a potential plant containing high iron, which is simple to find in Indonesia.

Aims: to determine the effectiveness of Moringa leaves supplementation in women of pro age.

Methods: This type of research is an experiment with experimental research with pre-post test control group design. The sample was 119 subjects collected using purposive sampling according to the inclusion criteria. The study subjects were divided into 3 treatment groups: supplementation of Ferrous sulfate tablets 30 mg per day (Group P0); 3000 mg Moringa leaf capsules three times a day (3 x 1000 mg) (Group P1); and Moringa leaf capsules at a dose of 3000 mg three times a day (3 x 1000 mg) plus 30 mg ferrous sulfate tablets once daily (Group P2) for 60 days, then hemoglobin (Hb) levels were re-evaluated.

Result: The Friedman test showed a mean Hb difference between the three measurement groups, which was statistically significant with p <0.05. The treatment group with P2 had the highest value of 4.74, followed by P1 and P0 of 4.71 and 4.65.

Conclusion: Supplementation of Moringa leaf capsules at a dose of 3000 mg for 60 days may increase Hb levels in women of reproductive age with iron deficiency anemia.

References

  1. Departemen Kesehatan Republik Indonesia. Profil Kesehatan Indonesia Tahun 2020. Departemen Kesehatan Republik Indonesia; 2021. https://www.kemkes.go.id/downloads/resources/download/pusdatin/profil-kesehatan-indonesia/Profil-Kesehatan-Indonesia-Tahun-2020.pdf
  2. Suega K, Elyani I. Iron defciency in women of reproductive age of Pekutatan Subdistrict, Jembrana, Regency Bali: association with demographic profles. Bali Med J. 2017;6(1):60-67. doi:10.15562/bmj.v6i1.432
  3. Stephen G, Mgongo M, Hussein Hashim T, Katanga J, Stray-Pedersen B, Msuya SE. Anaemia in Pregnancy: Prevalence, Risk Factors, and Adverse Perinatal Outcomes in Northern Tanzania. Anemia. 2018;2018:1846280. doi:10.1155/2018/1846280
  4. James AH. Iron Deficiency Anemia in Pregnancy. Obstet Gynecol. 2021;138(4):663-674. doi:10.1097/AOG.0000000000004559
  5. Sudikno S, Sandjaja S. Prevalensi Dan Faktor Risiko Anemia Pada Wanita Usia Subur Di Rumah Tangga Miskin Di Kabupaten Tasikmalaya Dan Ciamis, Provinsi Jawa Barat. Indones J Reprod Health. 2016;7(2):71-82. Accessed June 10, 2023. https://www.neliti.com/publications/107942/
  6. Fitriani F. Gambaran Umum Asupan Zat Besi (Fe) Pada Wanita Usia Subur (WUS) Suku Madura Di Kecamatan Kedungkandang Kota Malang. Sarjana. Universitas Brawijaya; 2015. Accessed June 10, 2023. http://repository.ub.ac.id/id/eprint/125381/
  7. Munir M. Impact of Dried Moringa Oleifera Leaves as Value Added Supplement in Enhancing Hemoglobin Status of Reproductive Aged Females of Low Socio-Economic Group. clinicaltrials.gov; 2018. Accessed June 8, 2023. https://clinicaltrials.gov/ct2/show/NCT03514472
  8. Suzana D, Suyatna FD, Azizahwati, Andrajati R, Sari SP, Mun’im A. Effect of moringa oleifera leaves extract against hematology and blood biochemical value of patients with iron deficiency anemia. J Young Pharm. 2017;9(1):S79-S84. doi:10.5530/jyp.2017.1s.20
  9. Mustapa Y, Hadju V, Indriasari R, Hidayanti H, Sirajuddin S, Russeng SS. The Effect of Moringa oleifera to Hemoglobin Levels of Preconception Women in the Health Center Tibawa District Tibawa, Gorontalo. Open Access Maced J Med Sci. 2020;8(T2):104-108. doi:10.3889/oamjms.2020.5201
  10. Fachriyah E, Kusrini D, Haryanto IB, Wulandari SMB, Lestari WI, Sumariyah S. Phytochemical Test, Determination of Total Phenol, Total Flavonoids and Antioxidant Activity of Ethanol Extract of Moringa Leaves (Moringa oleifera Lam). J Kim Sains Dan Apl. 2020;23(8):290-294. doi:10.14710/jksa.23.8.290-294
  11. Hikmah N, Nontji W, Hadju V. Teh daun kelor (moringa oleifera tea) terhadap kadar hemoglobin dan hepcidin ibu hamil. J Kebidanan. 2021;10(2):181-189. doi:10.26714/jk.10.2.2021.181-189
  12. Role Of Moringa Oleifera Leaf Extract In Increasing Hemoglobin Levels In Pregnant Rats With Anemia | Journal of Health Sciences. Accessed June 10, 2023. https://journal2.unusa.ac.id/index.php/JHS/article/view/1296
  13. The effect of moringa leaf extracton increasing hemoglobin and bodyweight in post-disaster pregnant women | Enfermería Clínica. Accessed June 10, 2023. https://www.elsevier.es/en-revista-enfermeria-clinica-35-articulo-the-effect-moringa-leaf-extracton-S1130862120301443
  14. Eniwati E, Ps RD, Utama WT. Hubungan Asupan Protein Nabati dengan Kadar Hemoglobin Pada Wanita Usia Remaja Vegan. Med Prof J Lampung. 2019;9(2):224-227. doi:10.53089/medula.v9i2.262
  15. Higasa S, Tsujimura M, Hiraoka M, et al. Polymorphism of glutathione S-transferase P1 gene affects human vitamin C metabolism. Biochem Biophys Res Commun. 2007;364(3):708-713. doi:10.1016/j.bbrc.2007.10.076

How to Cite

Siagian, C., Djogo, M. F., Nahak, M. M., Tedjasulaksana, R., Manek, A. E., Sormin, E., & Levina Augusta Geraldine Pieter. (2023). Supplementation of Moringa (Moringa oleifera) leaf capsules on hemoglobin levels in women of reproductive age with iron deficiency anemia in Malaka regency, Nusa Tenggara Timur, Indonesia. Bali Medical Journal, 12(3), 2383–2385. https://doi.org/10.15562/bmj.v12i3.4581

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Carmen Siagian
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Maria Fransisca Djogo
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Maria Martina Nahak
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Regina Tedjasulaksana
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Alfridus Emanuel Manek
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Elferida Sormin
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Levina Augusta Geraldine Pieter
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