ORIGINAL ARTICLE

Correlation of Estradiol Serum Levels with Classification of Osteoporosis Risk OSTA (Osteoporosis Self-Assessment Tools for Asian) in Menopause Women

Eva Maya Puspita , M. Fidel Ganis Siregar, Ichwanul Adenin

Eva Maya Puspita
Department of Obstetrics and Gynecology, H. Adam Malik General Hospital, North Sumatra University, Medan, Indonesia. Email: [email protected]

M. Fidel Ganis Siregar
Department of Obstetrics and Gynecology, H. Adam Malik General Hospital, North Sumatra University, Medan, Indonesia

Ichwanul Adenin
Department of Obstetrics and Gynecology, H. Adam Malik General Hospital, North Sumatra University, Medan, Indonesia
Online First: January 10, 2017 | Cite this Article
Puspita, E., Siregar, M., Adenin, I. 2017. Correlation of Estradiol Serum Levels with Classification of Osteoporosis Risk OSTA (Osteoporosis Self-Assessment Tools for Asian) in Menopause Women. Bali Medical Journal 6(1): 52-55. DOI:10.15562/bmj.v6i1.379


Background: In postmenopausal women, decreasing estrogen levels is a marker of ovarian dysfunction. Hypoestrogenic state has known increasing the risk of osteoporosis. Objective: To determine the correlation between estradiol serum levels with classification of osteoporosis risk OSTA (Osteoporosis Self-Assessment Tools for Asian) in menopausal women. Methods: This study was case series study which examined estradiol serum in menopausal women by ELISA and assess the osteoporosis risk using osteoporosis risk classification OSTA. Total 47 samples was collected at Dr. H.Adam malik, dr. Pirngadi, and RSU Networking in Medan. This research was conducted from May to December 2016. Data were statistically analyzed, and presented with Spearman test. Results: In this study, we found the mean levels of estradiol in menopausal women was 18.62 ± 16.85 ng / ml with OSTA osteoporosis risk score of 2.09 ± 2.45. There was a significant positive correlation between estradiol and risk of osteoporosis OSTA with correlation coefficient r = 0.825 and p <0.05. Conclusion: There is a strong positive correlation between serum levels of estradiol with OSTA osteoporosis risk assessment in menopausal women.

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