Skip to main content Skip to main navigation menu Skip to site footer

Evaluating Low Values of Early Diastolic Velocity (e’) as a Predictor of Major Cardiovascular Events in Patients with Acute Myocardial Infarction

  • Vianney Tedjamulia ,
  • Ida Bagus Rangga Wibhuti ,
  • Ida Sri Iswari ,
  • Ketut Badjra Nadha ,

Abstract

Background: Effective risk stratification is an integral part of acute myocardial infarction (AMI) management. Meanwhile, the stratification system should be performed by using easy instruments or methods, where appropriate management, intervention timing, and prognosis can be determined. A previous study established acute ischemia implicate the diastolic function of the left ventricle. In this situation, echocardiography is an easy-to-use and effective diagnostic tool. Therefore, this study evaluates left ventricular diastolic function using the tissue Doppler imaging (TDI) method to analyze the reduction of early diastolic velocity (e’) as a predictor for numerous cardiovascular events in patients with AMI.

Method: The study design was an observational study with a prospective cohort design. The data for the septal and lateral Early Diastolic Velocities (e’) was acquired using the transthoracic echocardiography procedure on AMI patients. The Hazard Ratio (HR) and survival curve from prognostic factors of major adverse cardiovascular events were also produced.

Results: There were 66 patients diagnosed with AMI. The median was 6.625cm/s, and the cut-off point was to determine the decreasing or abnormal mean e’. Subsequently, this value at RR 2.8 was shown by the multivariate analysis via Cox regression as an independent factor of major adverse cardiovascular events.

Conclusion: Decreased means e’ has been proven as an independent predictor of major adverse cardiovascular events in hospitalized patients with AMI.

References

  1. Mullasari AS, Balaji P, Khando T. Managing complications in acute myocardial infarction. J Assoc Physicians India. 2011;59 Suppl:43–8.
  2. Collet J-P, Thiele H, Barbato E, Barthélémy O, Bauersachs J, Bhatt DL et al. Corrigendum to: 2020 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: The Task Force for the management of acute coronary syndromes in patients presenting without persistent ST-s. Eur Heart J. 2021;42(23):2298. Available from: http://dx.doi.org/10.1093/eurheartj/ehab285
  3. Anderson JL, Adams CD, Antman EM, Bridges CR, Califf RM, Casey DE, et al. 2012 ACCF/AHA Focused Update Incorporated Into the ACCF/AHA 2007 Guidelines for the Management of Patients With Unstable Angina/Non–ST-Elevation Myocardial Infarction. J Am Coll Cardiol. 2013;61(23):e179–347. Available from: http://dx.doi.org/10.1016/j.jacc.2013.01.014
  4. Zheng S, Lyu J, Han D, Xu F, Li C, Yang R, et al. Establishment of a prognostic model based on the Sequential Organ Failure Assessment score for patients with first-time acute myocardial infarction. J Int Med Res. 2021;49(5):3000605211011976.
  5. Nagueh SF, Smiseth OA, Appleton CP, Byrd BF, Dokainish H, Edvardsen T, et al. Recommendations for the Evaluation of Left Ventricular Diastolic Function by Echocardiography: An Update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. J Am Soc Echocardiogr. 2016;29(4):277–314. Available from: http://dx.doi.org/10.1016/j.echo.2016.01.011
  6. Maragiannis D, Nagueh SF. 14 - Evaluation of Right Ventricular Diastolic Function. In: Klein AL, Garcia MJBT-D (Second E, editors. Philadelphia: Elsevier; 2021. p. 180–90. Available from: https://www.sciencedirect.com/science/article/pii/B9780323640671000140
  7. Flachskampf FA, Schmid M, Rost C, Achenbach S, DeMaria AN, Daniel WG. Cardiac imaging after myocardial infarction. Eur Heart J. 2010;32(3):272–83. Available from: http://dx.doi.org/10.1093/eurheartj/ehq446
  8. Naqvi TZ, Padmanabhan S, Rafii F, Hyuhn HK, Mirocha J. Comparison of Usefulness of Left Ventricular Diastolic Versus Systolic Function as a Predictor of Outcome Following Primary Percutaneous Coronary Angioplasty for Acute Myocardial Infarction. Am J Cardiol. 2006;97(2):160–6. Available from: http://dx.doi.org/10.1016/j.amjcard.2005.08.022
  9. Thygesen K, Alpert JS, Jaffe AS, Chaitman BR, Bax JJ, Morrow DA, et al. Fourth Universal Definition of Myocardial Infarction (2018). J Am Coll Cardiol. 2018;72(18):2231–64. Available from: http://dx.doi.org/10.1016/j.jacc.2018.08.1038
  10. Hick K, Tcheng J, Bozkurt B, Chaitman B, Cutlip D, Farb A et al. 2014 ACC/AHA Key Data Elements and Definitions for Cardiovascular Endpoint Events in Clinical Trials. J Nucl Cardiol. 2015;22(5):1041–144. Available from: http://dx.doi.org/10.1007/s12350-015-0209-1
  11. Plana J, Desai MY, Klein AL. Assessment of Diastolic Function by Echocardiography [Internet]. The Practice of Clinical Echocardiography. Elsevier; 2007. p. 237–61. Available from: http://dx.doi.org/10.1016/b978-1-4160-3640-1.50015-0
  12. Juras R. Estimates of Intraclass Correlation Coefficients and Other Design Parameters for Studies of School-Based Nutritional Interventions. Eval Rev. 2016;40(4):314–33. Available from: http://dx.doi.org/10.1177/0193841x16675223
  13. Tam E, Murthy Sandhya, Piña I. 7 - General Principles, Clinical Definition, Epidemiology, and Pathophysiology. In: Klein AL, Garcia MJBT-D (Second E, editors. Philadelphia: Elsevier; 2021. p. 86–92. Available from: https://www.sciencedirect.com/science/article/pii/B9780323640671000073
  14. Temporelli PL, Giannuzzi P, Nicolosi GL, Latini R, Franzosi MG, Gentile F, et al. Doppler-derived mitral deceleration time as a strong prognostic marker of left ventricular remodeling and survival after acute myocardial infarction. J Am Coll Cardiol. 2004;43(9):1646–53. Available from: http://dx.doi.org/10.1016/j.jacc.2003.12.036
  15. Zipes D, Libby P, Braunwald E, Bonow R, Mann D, Tomaselli G. Braunwald’s Heart Disease: A Textbook of Cardiovascular Medicine. 11th ed. Elsevier Inc; 2019.
  16. Su G, Mi S, Tao H, Li Z, Yang H-X, Zheng H, et al. Impact of admission glycemic variability, glucose, and glycosylated hemoglobin on major adverse cardiac events after acute myocardial infarction. Diabetes Care. 2013/01/24. 2013;36(4):1026–32. Available from: https://pubmed.ncbi.nlm.nih.gov/23349547

How to Cite

Vianney Tedjamulia, Ida Bagus Rangga Wibhuti, Ida Sri Iswari, & Ketut Badjra Nadha. (2022). Evaluating Low Values of Early Diastolic Velocity (e’) as a Predictor of Major Cardiovascular Events in Patients with Acute Myocardial Infarction. Bali Medical Journal, 11(1), 418–424. https://doi.org/10.15562/bmj.v11i1.3360

HTML
0

Total
0

Share

Search Panel

Vianney Tedjamulia
Google Scholar
Pubmed
BMJ Journal


Ida Bagus Rangga Wibhuti
Google Scholar
Pubmed
BMJ Journal


Ida Sri Iswari
Google Scholar
Pubmed
BMJ Journal


Ketut Badjra Nadha
Google Scholar
Pubmed
BMJ Journal