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Meningoencephalitis due to SARS-CoV-2 and tuberculosis co-infection: a case report from Indonesia

Abstract

Introduction: The novel coronavirus which firstly detected in December 2019 in Wuhan, China, has been known to cause neurological dysfunction either by directly or indirectly infecting the brain.

Case: We are reporting a case of meningoencephalitis due to co-infection of M. tuberculosis and SARS-CoV-2 in a hospital in Indonesia. A 26-year-old gentleman working as a courier in a Sars-Cov-2 red zone without adequate protection complained frequent headaches since a month to admission. M. tuberculosis was detected on very low level by GenXpert® and rapid test for SARS-CoV-2 was nonreactive. Repeated GenXpert® showed detected M. tuberculosis with undetected rifampicin resistance. Subsequent CSF SARS-CoV-2 PCR was positive although the oropharyngeal swab was negative.

Conclusion: The report of pulmonary co-infection of TB and SARS-COV-2 has been published, however, to our best knowledge there has been no report of neurological co-infection to date. We are reporting the report of CNS co-infection from our country.

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How to Cite

Retnaningsih, R., Purwaamijaya, B., Tugasworo, D., Andhitara, Y., Ardhini, R., Kurnianto, A., Afany, N., Bunyamin, J., Utami, F. S., Sogata, I. A., & Hairuzaman, H. (2021). Meningoencephalitis due to SARS-CoV-2 and tuberculosis co-infection: a case report from Indonesia. Bali Medical Journal, 10(2), 673–676. https://doi.org/10.15562/bmj.v10i2.2235

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