ORIGINAL ARTICLE

Seizure free status as a good predictor for quality of life of temporal lobe epilepsy patients after amygdalohippocampectomy

Muhamad Thohar Arifin , Ashari Ashari, Surya Pratama Brilliantika, Jacob Bunyamin, Hardian Hardian, Happy Kurnia Brotoarianto, Alifiati Fitrikasari, Zainal Muttaqin

Muhamad Thohar Arifin
Department of Neurosurgery, Faculty of Medicine, Universitas Diponegoro, Semarang City, Central Java Province, Indonesia. Email: [email protected]

Ashari Ashari
Department of Neurosurgery, Faculty of Medicine, Universitas Diponegoro, Semarang City, Central Java Province, Indonesia

Surya Pratama Brilliantika
Department of Neurosurgery, Faculty of Medicine, Universitas Diponegoro, Semarang City, Central Java Province, Indonesia

Jacob Bunyamin
Department of Neurosurgery, Faculty of Medicine, Universitas Diponegoro, Semarang City, Central Java Province, Indonesia

Hardian Hardian
Department of Physiology, Faculty of Medicine, Universitas Diponegoro, Semarang City, Central Java Province, Indonesia

Happy Kurnia Brotoarianto
Department of Neurosurgery, Faculty of Medicine, Universitas Diponegoro, Semarang City, Central Java Province, Indonesia

Alifiati Fitrikasari
Department of Psychiatry, Faculty of Medicine, Universitas Diponegoro, Semarang City, Central Java Province, Indonesia

Zainal Muttaqin
Department of Neurosurgery, Faculty of Medicine, Universitas Diponegoro, Semarang City, Central Java Province, Indonesia
Online First: December 01, 2020 | Cite this Article
Arifin, M., Ashari, A., Brilliantika, S., Bunyamin, J., Hardian, H., Brotoarianto, H., Fitrikasari, A., Muttaqin, Z. 2020. Seizure free status as a good predictor for quality of life of temporal lobe epilepsy patients after amygdalohippocampectomy. Bali Medical Journal 9(3): 855-858. DOI:10.15562/bmj.v9i3.2141


Background:  The aim of epilepsy surgery is to improve the quality of life of people with epilepsy. Temporal lobe epilepsy (TLE) is the most common form of intractable epilepsy with a risk of low quality of life due to uncontrolled seizures. In this study, we evaluated the quality of life among TLE patients who underwent amygdalohippocampectomy between those who were free from seizure and those who were not.

Methods: This was a cross-sectional observational study. The postoperative quality of life was measured by QOLIE-31 questionnaire followed-up at least 12 months since the surgery.

 

Results: Among 31 patients, 21 patients (67.7%) were free from seizures after 12 months of follow-up. We observed significantly higher quality of life of those seizure-free patients either as overall quality of life (p=0.001) or among domains such as seizure anxiety (p=0.003), emotional well-being (p<0.001), fatigue (p<0.001), cognition (p=0.002), medication effects (p=0.01) and social function (p<0.001).

Conclusion:  TLE patients who were seizure-free had better quality of life compared to those who were not after amygdalohippocampectomy.

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Ashari A, Arifin MT, Hardian, Muttaqin Z, Brotoarianto HK, Fitrikasari A. Comparison in quality of life in temporal lobe epilepsy with seizure free status compared to non seizure free status after amygdalohippocampectomy. Bachelor Thesis Diponegoro University; 2012. Available from: http://eprints.undip.ac.id/37394/1/ASHARI_G2A008032_LAP._KTI.pdf Accessed September 26, 2020


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