CASE REPORT

Penile gangrene as a priapism sequele due to Chronic Myeloid Leukemia (CML): the first report in Indonesia

Deddy Rasyidan Yulizar, Eka Putri Maulani , Heru Prasetya, Hendra Sutapa, Eka Yudha Rahman

Deddy Rasyidan Yulizar
Urology Division, Surgery Department, Faculty of Medicine, Universitas Lambung Mangkurat, Ulin General Hospital, Banjarmasin, Indonesia

Eka Putri Maulani
Resident of The Surgery Department, Faculty of Medicine, Universitas Lambung Mangkurat, Ulin General Hospital, Banjarmasin, Indonesia. Email: [email protected]

Heru Prasetya
Urology Division, Surgery Department, Faculty of Medicine, Universitas Lambung Mangkurat, Ulin General Hospital, Banjarmasin, Indonesia

Hendra Sutapa
Urology Division, Surgery Department, Faculty of Medicine, Universitas Lambung Mangkurat, Ulin General Hospital, Banjarmasin, Indonesia

Eka Yudha Rahman
Urology Division, Surgery Department, Faculty of Medicine, Universitas Lambung Mangkurat, Ulin General Hospital, Banjarmasin, Indonesia
Online First: April 01, 2021 | Cite this Article
Yulizar, D., Maulani, E., Prasetya, H., Sutapa, H., Rahman, E. 2021. Penile gangrene as a priapism sequele due to Chronic Myeloid Leukemia (CML): the first report in Indonesia. Bali Medical Journal 10(1): 108-110. DOI:10.15562/bmj.v10i1.2125


Background: Priapism is defined as a prolonged erection of the penis lasting over 6 hours in the absence of sexual stimulation. Priapism is divided into two types, Low-Flow (ischemic priapism) and High-Flow (trauma). This case study aims to evaluate penile gangrene as a priapism sequele due to Chronic Myeloid Leukemia (CML) as the first report in Indonesia.

Case Presentation: A 45-years old male patient admitted at Muara Teweh hospital before referred to Ulin Hospital presented with Fournier gangrene with unconfirmed leukemia as comorbidities used in this case report. In his medical history, “Snake Maneuver Shunting” has been carried out in this patient as an indication for priapism lasting more than 24 hours.

Conclusion: Hyperleukocytosis is thought to be the cause of priapism in patients with leukemia. Leukostasis is the most common medical emergency seen on CML patients in blast crisis.

References

Van der Horst C, Stuebinger H, Seif C, Melchior D, Martínez-Portillo FJ, Juenemann KP. Priapism - etiology, pathophysiology and management. Int Braz J Urol. 2003;29(5):391-400.

Broderick GA, Kadioglu A, Bivalacqua TJ, Ghanem H, Nehra A, Shamloul R. Priapism: pathogenesis, epidemiology, and management. J Sex Med. 2010;7(1 Pt 2):476-500.

Ajape AA, Bello A. Penile gangrene: an unusual complication of priapism in a patient with bladder carcinoma. J Surg Tech Case Rep. 2011;3(1):37-39.

Ergenc H, Varım C, Karacaer C, Çekdemir D. Chronic myeloid leukemia presented with priapism: Effective management with prompt leukapheresis. Niger J Clin Pract. 2015;18(6):828-830.

Kwok B, Varol C. Priapism and penile gangrene due to thrombotic thrombocytopenic purpura. Urology. 2010;75(1):71-72.

Ajape AA, Bello A. Penile gangrene: an unusual complication of priapism in a patient with bladder carcinoma. J Surg Tech Case Rep. 2011;3(1):37-39. doi:10.4103/2006-8808.78470

Keoghane SR, Sullivan ME, Miller MA. The aetiology, pathogenesis and management of priapism. BJU Int. 2002;90(2):149-154.

Bochinski DJ, Dean RC, Lue TF. Erectile dysfunction and priapism. Nat Clin Pract Urol. 2004;1(1):49-53.

Badmus TA, Adediran IA, Adesunkanmi AR, Katung IA. Priapism in southwestern Nigeria. East Afr Med J. 2003;80(10):518-524.

Savona M, Talpaz M. Chronic myeloid leukemia: changing the treatment paradigms. Oncology (Williston Park). 2006;20(7):707-724.

Ponniah A, Brown CT, Taylor P. Priapism secondary to leukemia: effective management with prompt leukapheresis. Int J Urol. 2004;11(9):809-810.

Tazi I. Priapism as the first manifestation of chronic myeloid leukemia. Ann Saudi Med. 2009;29(5):412.

Steinhardt GF, Steinhardt E. Priapism in children with leukemia. Urology. 1981;18(6):604-606.


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