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Potential development of turmeric extract nanoparticles as a topical anti-inflammatory agent

Nyoman Suryawati , I Made Jawi

Nyoman Suryawati
Dermatology and Venereology Department, Faculty of Medicine, Universitas Udayana-Sanglah Hospital, Denpasar, Bali-Indonesia. Email: [email protected]

I Made Jawi
Pharmacology Department, Faculty of Medicine, Universitas Udayana, Bali-Indonesia
Online First: October 21, 2020 | Cite this Article
Suryawati, N., Jawi, I. 2020. Potential development of turmeric extract nanoparticles as a topical anti-inflammatory agent. Bali Medical Journal 9(3): 573-578. DOI:10.15562/bmj.v9i3.2026


Turmeric is the most commonly studied herbal ingredient because it has antioxidant, anti-inflammatory, antimicrobial, and anticancer activity. Considering that most inflammatory skin diseases are localized, it is considered that the topical application of turmeric extract can be beneficial because it has a local effect on the skin. The topical application of turmeric extract has limitations because the active ingredient content of curcumin (CUR) has poor solubility in water, low absorption, and rapid elimination of metabolites, which results in low bioavailability of the drug. Recent studies have focused more on nanoparticle formulations that can improve the stability and bioavailability of CUR.

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