Healthy, happy, success and long life are everyone's dream of being. To have these, proper nutrition is one of the basic needs that must be metâ€”food composing of nutrients and non-nutrients that will influence the quality of food. Hence, Food must meet four conditions to be said as healthy food. It has to be adequate, balance in the composition of nutrients, calorie in control, and free or at least within the safety level of health hazard components. Yet, food does not affect directly on oneâ€™s health but the diet, though it takes time from unhealthy habit into getting the disease or vice versa.Â Since food has many functions in human life, moderation and variety becoming very important to compose a healthy diet. If these six principals are put into the habit, then fit, and well-being can be promised so far unless some other risk factors can affect health.Â Water has a crucial role in supporting the body function, and human cannot avoid drink in daily life. Still, beverage drinks can be easily slipped into the hazardous substrate that will influence on health. Knowledge on nutrigenomic is worth to be applied to have more on the personal approach of how food and diet can affect health.