Comparison of insulin therapy outcomes (satisfaction with treatment, pain during injection, follow-up) in patients using insulin pen and insulin infusion with syringe

Sanaz Azami , Mosayyeb Mozafari, Hassan Pourabdollah

Sanaz Azami
Ilam University of Medical Sciences. Email: [email protected]

Mosayyeb Mozafari
Ilam University of Medical Sciences

Hassan Pourabdollah
Ilam University of Medical Sciences
Online First: October 03, 2018 | Cite this Article
Azami, S., Mozafari, M., Pourabdollah, H. 2018. Comparison of insulin therapy outcomes (satisfaction with treatment, pain during injection, follow-up) in patients using insulin pen and insulin infusion with syringe. Bali Medical Journal 7(3). DOI:10.15562/bmj.v7i3.1009

The purpose of this study was to compare the effects of insulin therapy (satisfaction with treatment, injection pain, follow-up) in patients using insulin pen and insulin injection with syringe. The present study is a comparative and interventional type. The community of diabetics includes 11o subjects who have a case in Kermanshah Diabetes Clinic. The sample size was determined 82 people,on the basis of previous study of comparing two groups. The sample was randomly selected. Sample members were selected through simple random sampling. To gather the data, a researcher-made questionnaire of satisfaction with the treatment method and a general follow-up questionnaire GAS and scale of pain Vonkorff questionnaire, was used .The face and content validity of the questionnaires was evaluated and confirmed. The questionnaires were determined ausing Cronbach's alpha coefficient and was determined 80%for each of the three questionnaires. In this research to analyze the data, spss21 in two descriptive and inferential statistics were used. For descriptive statistics, Statistical Mean and standard deviation was used for demographic and descriptive information .In the inferential statistics, Kolmogorov-Smirnov test was used to test the normal variables and according to the result of this test, to test research hypotheses the t-test (paired t-test) and chi-square test were used. In general, independent t-test results  showed that there was a significant difference between the average satisfaction of the treatment method, the treatment and the pain of the injection time between the patients using pen and syringe injection (p <0.05) . The results of t-correlation test showed that there is a significant difference between the mean pain, injection time and the follow-up of the treatment in the two stages of the primary and secondary measurement (p<0.05). Also, the results of chi-square test showed that there is no significant relationship between  the demographic variables (gender, education level and age group) and the consequences of insulin therapy (satisfaction with treatment method, pain during injection, follow-up of treatment (p<0.05).


Ahmad NS, Ramli A, Islahudin F, Paraidathathu T. Medication adherence in patients with type 2 diabetes mellitus treated at primary health clinics in Malaysia. Patient Prefer Adherence. 2013; 7(1):525-530.

Al Momani M, Al Korashy H. Patient experience of nursing quality in a teaching hospital in Saudi Arabia. Iranian journal of public health. 2012; 41(8):42.

Asakura T, Seino H, Nakano R, et al. A comparison of the handling and accuracy of syringe and vial versus prefilled insulin pen FlexPen. Diabetes Technol Ther 2009; 11:657–61.

Bruce DG, Davis WA, Davis TM. Longitudinal Predictors of Reduced Mobility and Physical Disability in Patients with Type 2 Diabetes the Fremantle Diabetes Study. Diabetes care. 2005; 28(10):2441-7.

Chaturvedi N. The burden of diabetes and itscomplications: trends and implications for intervention. Diabetes Research and Clinical Practice. 2007; 76(3):S3-S12..

Dormandy JA, Charbonnel B, Eckland DJ, Erdmann E, Massi-Benedetti M, Moules IK, et al. Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (PROspective pioglitAzone Clinical Trial In macroVascular Events): a randomised controlled trial. The Lancet 2005; 366(9493):1279-1289.

Evans M, Schumm-Draeger PM, Vora J, King AB. A review of modern insulin analogue pharmacokinetic and pharmacodynamic profiles in type 2 diabetes: Improvements and limitations. Diabetes Obes Metab. 2011; 13:677-684.

Estella M. Davis, Carla M. Christensen, Kelly K. Nystrom, Pame la A. Foral, and Chris Destache (2008). Patient satisfaction and costs associated with insulin administered by pen device or syringe during hospitalization. Am J Health Syst Pharm; 65:1347–57.

Faro B. The effects of diabetes on adolescent's quality of life. Pediatric Nursing 1999. 24:247-54.

Garsia-Perez LE, Dilla T. Adherence to therapies in patients with type 2 diabetes. Diabetes Ther. 2013; 4(2):175-194.

Hays, R. D.(1994). The medical outcomes study (mos) measures of patient adherence. J Behav Med, 17:361-72.

Lajara R, Guerrero G, Thurman J. Healthcare professional and patient perceptions of a new prefilled insulin pen versus vial and syringe. Expert Opin Drug Deliv 2012; 9:1181–96.

Lee J-A, Park JH. Control of hypertension and diabetes among adults aged over 40 years with or without physical disabilities. International Journal on Disability and Human Development. 2015; 14(2):151-60.

Mmyshy N, Behroozi Shad F, Mohagheghi MA, Eftekhari Z,Shahabi Z. Nurses’ Knowledge and attitudes toward pain relief in oncologic patients.J Tehran Univ Med Sci (Hayat) 2007; 12(2) :23-32 (Persian(.

Molife C, Lee LJ, Shi L, et al. Assessment of patient-reported outcomes of insulin pen devices versus conventional vial and syringe. Diabetes Technol Ther 2009; 11:529–38.

Pfutzner A, Bailey T, Campos C, et al. Accuracy and preference assessment of prefilled insulin pen versus vial and syringe with diabetes patients, caregivers, and healthcare professionals. Curr Med Res Opin 2013; 29:475–81.

Schulmeister L, Quiett K, Mayer K, editors. Quality of life, quality of care, and patient satisfaction: perceptions of patients undergoing outpatient autologous stem cell transplantation. Oncology nursing forum; 2009.

Vonkorff, M., Ormel, J.,keefe, F.J.,& Dworkin, S. F. (1992). Grading the severity of chronic pain. Pain, 50(2), pp. 133-149.

Young BA, Lin E, Von Korff M, Simon G, Ciechanowski P, Ludman EJ, et al. Diabetes complications severity index and risk of mortality, hospitalization, and healthcare utilization. The American journal of managed care. 2008; 14(1):15.

No Supplementary Material available for this article.
Article Views      : 0
PDF Downloads : 0